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This book aims to synthesis of some new heterocyclic compounds containing benzothiazole moiety which can be used as biological evaluation. The work divided into three parts followed by antimicrobial screening for some synthesized compounds. Part 1: Utility of N-(benzothiazol-2-yl)-2-cyanoacetamide in heterocyclic synthesis. Part 2: Utility of Enaminonitrile in heterocyclic synthesis. Part 3: Utility of 2-oxo-2H-pyrimido[2,1-b]benzothiazole-3-carbonitrile in heterocyclic Synthesis. The biological evaluation of some new synthetic compounds against some types of bacteria, fungi and comparison of some medicines in the Egyptian market was studied. The study proved that there are some compounds with high efficiency compared with the selected drugs.
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