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This book provides a comprehensive exploration of Nicotinamide N-Methyltransferase (NNMT), an enzyme with far-reaching implications across various fields of biomedicine. It delves into the multifaceted roles of NNMT in neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's, unraveling its impact on epigenetic regulation and metabolic homeostasis. The book also examines NNMT's significance in cardiovascular diseases, including atherosclerosis and heart failure, and its potential as a therapeutic target. Furthermore, it discusses NNMT's critical role in cancer metabolism and progression. With contributions from leading experts, this volume compiles cutting-edge research, offering valuable insights for researchers and clinicians. It highlights NNMT's potential as a therapeutic target and its significance in energy metabolism and disease progression, making it a vital resource for those engaged in NNMT research and its clinical applications. This work was supported by the National Natural Science Foundation of China (32260014) and Social Science Planning Project of Jiangxi Province, China (19WT94).
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