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This volume provides§a sound basis for the molecular investigation of NLR function in health and§disease. Chapters focus on of innate immune receptors, "atypical"§inflammasomes, biochemical and novel bioluminescence§techniques for the measurement of IL-1b,§bioluminescent probe, biochemical and microscopy§techniques, techniques to measure caspase-1 activation, cell§free systems for the study of inflammasome function, and inflammasome§activation. Written in the highly successful Methods§in Molecular Biology series format, chapters include introductions to their§respective topics, lists of the necessary materials and reagents, step-by-step,§readily reproducible laboratory protocols, and tips on troubleshooting and§avoiding known pitfalls.§§Authoritative§and cutting-edge, NLR Proteins: Methods§and Protocols aims to ensure successful results in the further study of§this vital field.§
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