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Nanotheranostics and Precision Oncology provides an in-depth review of the latest advancements in Precision Oncology, with a particular emphasis on nanotheranostics. The book begins with an overview of cancer biology, elucidating the genetic underpinnings of oncogenesis, as well as the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance—the foremost challenge in cancer care. In 28 chapters it explores the pivotal role of precision medicine in overcoming drug resistance, the significance of biomarkers, the interpretation of genetic analyses, and the shift towards personalized oncology. Furthermore, it examines the applications and mechanisms of nanotheranostics in cancer diagnosis and treatment, leading to their integration with Precision Oncology. Nanotheranostics and Precision Oncology outlines the design, mechanism, and impact of nanoprecision medicine in the context of cancer management. The final section considers the future of nanotheranostics in Precision Oncology and the challenges associated with translating these innovations from research to clinical practice. This book serves as a comprehensive guide for students, clinicians, researchers, and the pharmaceutical industry involved in the fields of nanomedicine, oncology, molecular biology, and precision medicine.