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Molecular Dynamics - Practical Application
- Mechanism underlying the resistance to prion diseases in rabbits : a technology review from MIT and in 7 languages
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In chemistry, physics, biophysics, biochemistry, biomedicine, bioinformatics, applied mathematics and theoretical physics, Molecular dynamics (MD) simulating physical movements of atoms and molecules is widely applied. Amber and Gromacs etc are very popular and practical MD packages. This book applies these packages to biomolecules and materials. It provides comprehensive MD materials and methods to put MD into actions. This book clearly has a value to MD simulation staff (in research or teaching) in the fields of chemistry, physics, biophysics, biochemistry, biomedicine, bioinformatics, applied mathematics and theoretical physics. This book fully illuminates MD application to prion proteins from many points of view. The author was awarded numerous world-wide impacts and fame for the successful MD application. Prion diseases can be caused by the body s own proteins not requiring either DNA, RNA, or both; they are "structural conformational" diseases so very proper to be studied by MD technologies. Rabbits, dogs and horses are reported to be immune to prion diseases. The author using MD technologies preliminarily revealed some surprising secrets from rabbits against prion diseases
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