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Inflammation is the complex pathophysiologic response of tissue injury or infection. Biochemical meadiators released during inflammation intensify and propagate the inflammatory response leading to organ dysfunction.Inflammatory mediators are soluble, diffusible molecules that act systematically & locally at the site of injury or infection.This book summarizes the critical role played by inflammatory mediators in the pathogenesis of acute & chronic inflammation.It is responsible to speculate the elucidation of the key mediators in inflammation , coupled with the discovery of specific inhibitors , would make it possible to develop clinically effective anti-inflammatory therapy.
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